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amoxicillin
GENERIC
NAME: amoxicillin
BRAND NAME:
Amoxil, Dispermox, Trimox
DRUG
CLASS AND MECHANISM: Amoxicillin is an antibiotic that
belongs to a class of antibiotics called penicillins.
Other members of this class include ampicillin (Unasyn),
piperacillin (Pipracil), ticarcillin (Ticar) and a
several others. These antibiotics all have a similar
mechanism of action. They do not kill bacteria, but they
stop bacteria from multiplying by preventing bacteria
from forming the walls that surround them. The walls are
necessary to protect bacteria from their environment and
to keep the contents of the bacterial cell together.
Bacteria cannot survive without a cell wall. Amoxicillin
is effective against many different bacteria including
H. influenzae, N. gonorrhoea, E. coli, Pneumococci,
Streptococci, and certain strains of Staphylococci.
PRESCRIPTION: Yes.
GENERIC AVAILABLE: Yes.
PREPARATIONS: Capsules: 250 and
500 mg. Tablets: 500 and 875 mg. Chewable tablets: 125,
200, 250, and 400 mg. Powder for suspension: 50 mg/ml ;
125 , 200, 250, and 400 mg/5 ml. Tablets for suspension:
200 and 400 mg
STORAGE: Store Amoxil capsules as
well as 125 and 250 mg dry powder at or below 20°C
(68°F); tablets, chewable tablets, as well as 200 and
400 mg dry powder at or below 25°C(77°F). Store Trimox
capsules and unreconstituted powder at or below 20°C
(68°F) and chewable tablets at room temperature 15°-30°C
(59°-86°F). Powder that has been mixed with water should
be discarded after 14 days. Refrigeration is preferred
but not required for powder mixed with water.
PRESCRIBED FOR: Amoxicillin is
used to treat infections due to organisms that are
susceptible to the effects of amoxicillin. Common
infections that amoxicillin is used for include
infections of the middle ear, tonsils, throat, larynx
(laryngitis), bronchi (bronchitis), lungs (pneumonia),
urinary tract, and skin. It also is used to treat
gonorrhea.
DOSING: For most infections in
adults the dosing regimens for amoxicillin are 250 mg
every 8 hours, 500 mg every 8 hours, 500 mg every 12
hours or 875 mg every 12 hours, depending on the type
and severity of infection. For the treatment of adults
with gonorrhea the dose is 3 g given as one dose. For
most infections, children older than 3 months but less
than 40 kg are treated with 25 mg/kg/day in divided
doses every 12 hours, 20 mg/kg/day in divided doses
every 8 hours, 40 mg/kg/day in divided doses every 8
hours or 45 mg/kg/day in divided doses every 12 hours
depending on type and severity of the infection.
Amoxicillin
can be taken with or without food. DRUG INTERACTIONS:
Amoxicillin is rarely associated with important drug
interactions.
PREGNANCY: There are no adequate
studies of amoxicillin in pregnant women.
NURSING MOTHERS: Small amounts of
amoxicillin may be excreted in breast milk and may cause
diarrhea or allergic responses in nursing infants.
SIDE EFFECTS: Side effects
due to amoxicillin include diarrhea, dizziness,
heartburn, insomnia, nausea, itching, vomiting,
confusion, abdominal pain, easy bruising, bleeding, rash
and allergic reactions.
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