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cephalexin
GENERIC
NAME: cephalexin
BRAND NAME: Keflex,
Keftabs, Biocef
DRUG CLASS AND MECHANISM:
Cephalexin belongs to a class of antibiotics called
cephalosporins. They are similar to penicillin in action
and side effects. They stop or slow the growth of
bacterial cells by preventing bacteria from forming the
cell wall that surrounds each cell. The cell wall
protects bacteria from the external environment and
keeps the contents of the cell together. Without a cell
wall bacteria are not able to survive. Bacteria that are
susceptible to cephalexin include Staphylococcus aureus,
Streptococcus pneumoniae, Haemophilus influenzae, E.
coli and several
others.
PRESCRIPTION:
Yes
GENERIC AVAILABLE:
Yes
PREPARATIONS: Tablets:
250 and 500 mg, and 1 g. Capsules: 250, 333,
500 and 750 mg. Powder for Suspension: 125, and 250
mg/5 ml.
STORAGE: Tablets and capsules
should be stored at room temperature, 15-30°C (59-86°F).
Suspensions should be refrigerated and discarded after
14 days.
PRESCRIBED FOR: Cephalexin is used
to treat infections caused by bacteria that are
susceptible to the effects of cephalexin. Common
infections that are treated with cephalexin include
infections of the middle ear, tonsils, throat, larynx
(laryngitis), bronchi (bronchitis) and pneumonia. It
also is used for treating urinary tract, skin and bone
infections.
DOSING: The dose of cephalexin for
adults is 1 to 4 grams in divided doses. Children are
treated with 25-100 mg/kg/day in divided doses.
DRUG INTERACTIONS: Serious
interactions of cephalexin with other drugs are
uncommon.
PREGNANCY: There are no good
studies of cephalexin in pregnant women. Based on
limited evidence, cephalosporins, including cephalexin,
appear to be safe when used during
pregnancy.
NURSING MOTHERS: Most
cephalosporins are excreted in breast milk. Nursing
mothers should avoid using cephalosporins or stop
breastfeeding while taking a
cephalosporin.
SIDE EFFECTS: The most common side
effects of cephalexin are diarrhea, nausea, abdominal
pain, vomiting, headaches, dizziness, skin rash, fever,
abnormal liver tests and vaginitis. Individuals who are
allergic to penicillin may also be allergic to
cephalexin. |