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Encephalitis literally means an
inflammation of the brain, but it usually refers
to brain inflammation caused by a virus. It's a
rare disease that only occurs in approximately
0.5 per 100,000 individuals - most commonly in
children, the elderly, and people with weakened
immune systems (i.e., those with HIV/AIDS or
cancer).

Before
After
Although several
thousand cases of encephalitis (also called
acute viral encephalitis or
aseptic encephalitis) are
reported to the Centers for Disease Control and
Prevention (CDC) every year, experts suspect
that many more may go unreported because the
symptoms are so mild.
Signs and
Symptoms
Symptoms in milder
cases of encephalitis usually
include:
- fever
- headache
- poor appetite
- loss of energy
- just a general
sick feeling
In more severe
cases of encephalitis, a person is more likely
to experience high fever and any of a number of
symptoms that relate to the central nervous
system including:
- severe headache
- nausea and
vomiting
- stiff neck
- confusion
- disorientation
- personality
changes
- convulsions
(seizures)
- problems with
speech or hearing
- hallucinations
- memory loss
- drowsiness
- coma
It's harder to
detect some of these symptoms in infants, but
there are still some important signs to look for
including:
- vomiting
- a full or bulging
soft spot (fontanel)
- crying that
doesn't stop or that seems worse when an infant
is picked up or handled in some way
- body stiffness
Because
encephalitis can follow or accompany common
viral illnesses, there are sometimes
characteristic signs and symptoms of these
illnesses beforehand. But often, the
encephalitis appears without warning.
Causes
Because
encephalitis can be caused by many types of
germs, the infection can be spread in several
different ways.
Of the many
different kinds of viruses that can cause
encephalitis, one of the most dangerous and the
most common cause of encephalitis is the herpes simplex virus (HSV).
HSV is the same virus that causes cold sores
around the mouth, but when it attacks the brain
it may be fatal in as many as half of newborns
who become infected and up to 28% of individuals
after the newborn period. Fortunately, HSV
encephalitis is very rare.
Encephalitis can be
a complication of Lyme disease transmitted by
ticks, or of
rabies spread by
rabid animals.
Mosquitoes can also
transmit the viruses for several types of
encephalitis, including West Nile encephalitis,
St. Louis encephalitis, and Western Equine
encephalitis. Over the last several years in the
United States, there's been concern about the
spread of West Nile virus, which is transmitted
to humans by mosquitoes that pick up the
virus by biting infected birds.
Milder forms of
encephalitis can follow or accompany common
childhood illnesses, including measles, mumps, chickenpox, rubella (German measles),
and mononucleosis.
Viruses like chickenpox spread mostly via the
fluids of the nose and throat, usually during a
cough or sneeze.
Less commonly,
encephalitis can result from a bacterial
infection, such as bacterial meningitis, or it may be a
complication of other infectious diseases like
syphilis. Certain
parasites, like toxoplasmosis, can also
cause encephalitis in people with weakened
immune systems.
Contagiousness
Brain inflammation
itself is not contagious, but
any of the various viruses that cause
encephalitis can be. Of course,
just because a child gets a certain virus does
not mean that he or she will
develop encephalitis. Still, to be safe,
children should avoid contact with anyone who
has encephalitis.
Prevention
Encephalitis
cannot be prevented except to
try to prevent the illnesses that may lead to
it. Encephalitis that may be seen with common
childhood illnesses like measles, mumps, and
chickenpox can be largely prevented through
proper immunization.
Have your child immunized according to the immunization schedule
recommended by your child's doctor. Children
should also avoid contact with anyone who
already has encephalitis.
In areas where
encephalitis can be transmitted by insect bites,
especially mosquitoes, children
should:
- Avoid being
outside at dawn and dusk (when mosquitoes are
most active).
- Wear protective
clothing like long sleeves and long pants.
- Use insect
repellent.
Also, all standing
water around your home should be drained,
including buckets, birdbaths, and flowerpots,
because these are breeding grounds for
mosquitoes.
Some things you can
do to avoid tick
bites:
- Limit your child's
contact with soil, leaves, and vegetation.
- Have your child
wear long-sleeved, light-colored shirts and long
pants.
- Check your child
and your pets frequently for ticks.
Duration
For most forms of
encephalitis, the acute phase of the illness
(when symptoms are the most severe) usually
lasts up to a week. Full recovery can take much
longer, often several weeks or
months.
Diagnosis
Doctors use several
tests to diagnose encephalitis,
including:
- imaging tests,
such as computed tomography (CT) scans or
magnetic resonance imaging (MRI), to check the
brain for swelling, bleeding, or other
abnormalities
- electroencephalogram (EEG),
which records the electrical signals in the
brain, to check for abnormal brain waves
- blood tests to confirm the
presence of bacteria or viruses in the blood,
and whether a person is producing antibodies
(specific proteins that fight infection) in
response to a germ
- lumbar puncture, also known
as a spinal tap, in which cerebrospinal fluid
(the fluid that surrounds the brain and spinal
cord) is checked for signs of infection
Treatment
Some children with
very mild encephalitis can be monitored at home,
but most will need care in a hospital, usually
in an intensive care unit. Doctors will
carefully monitor their blood pressure, heart
rate, and breathing, as well as their body
fluids, to prevent further swelling of the
brain.
Because antibiotics
aren't effective against viruses, they aren't
used to treat encephalitis. However, antiviral
drugs can be used to treat some forms of
encephalitis, especially the type caused by the
herpes simplex virus. Corticosteroids may also
be used in some cases to reduce brain swelling.
If a child is having seizures, anticonvulsants
may also be given.
Over-the-counter
(OTC) medications, like acetaminophen, can be
used to treat fever and headaches.
Most people with
encephalitis make a full recovery. In a small
percentage of cases, swelling of the brain can
lead to permanent brain damage and lasting
complications like learning disabilities, speech
problems, memory loss, or lack of muscle
control. Speech, physical, or occupational
therapy may be necessary in these
cases.
Rarely, if the
brain damage is severe, encephalitis can lead to
death. Infants younger than 1 year and adults
older than 55 are at greatest risk of death from
encephalitis.
When to Call Your Child's
Doctor
Call your child's
doctor if your child has a high fever, especially if he or
she also has a childhood illness (measles,
mumps, chickenpox) or is recovering from
one.
Seek immediate
medical attention if your child has any of the
following symptoms:
- severe headache
- convulsions
(seizures)
- stiff neck
- inability to look
at bright lights
- double vision
- difficulty walking
- problems with
speech or hearing
- difficulty moving
an arm or leg
- loss of sensation
anywhere in the body
- sudden personality
changes
- problems with
memory
- extreme drowsiness
or lethargy
- loss of
consciousness
If your infant has
any of the following symptoms, seek immediate
medical care:
- high fever or any
fever higher than 100.4 degrees Fahrenheit (38
degrees Celsius) in infants younger than 3
months of age
- fullness or
bulging in the soft spot
- any stiffness
- floppiness or
decreased tone
- lethargy
- poor appetite or
reduced feeding
- vomiting
- crying that won't
stop
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