hydrocodone/acetaminophen GENERIC NAME: hydrocodone/acetaminophen BRAND NAMES: Vicodin, Vicodin ES, Anexsia, Lorcet, Lorcet Plus, Norco DRUG CLASS AND MECHANISM: Hydrocodone is a narcotic pain-reliever and a cough suppressant, similar to codeine. The precise mechanism of pain relief by hydrocodone and other narcotics is not known. Acetaminophen is a non-narcotic analgesic (pain reliever) and antipyretic (fever reducer). Acetaminophen relieves pain by elevating the pain threshold. It reduces fever through its action on the heat regulating center of the brain. Frequently, hydrocodone and acetaminophen are combined to achieve pain relief, as in Vicodin and Lortab. For more information please see acetaminophen (Tylenol). PRESCRIPTION: yes GENERIC AVAILABLE: yes PREPARATIONS: Among the many brands the dose of acetaminophen ranges between 500 and 750 mg, and the dose of hydrocodone ranges between 2.5 and 10 mg. STORAGE: Store at room temperature, sealed, light- resistant container. PRESCRIBED FOR: Hydrocodone is prescribed for the relief of moderate to moderately severe pain. DOSING: Should be taken with food. DRUG INTERACTIONS: Hydrocodone can depress breathing, and is used with caution in elderly, debilitated patients and in patients with serious lung disease. Hydrocodone can impair thinking and the physical abilities required for driving or operating machinery. Alcohol and other sedatives, such as Xanax, can produce further brain impairment and even confusion when combined with hydrocodone. Hydrocodone is generally avoided in children. Hydrocodone may be habit forming. Mental and physical dependence can occur, but are unlikely when used for short-term pain relief. PREGNANCY: Hydrocodone is generally avoided in pregnant women. NURSING MOTHERS: Hydrocodone is generally avoided in nursing mothers. SIDE EFFECTS: The most frequent adverse reactions include lightheadedness, dizziness, sedation, nausea, and vomiting. Other side effects include drowsiness, constipation, and spasm of the ureter, which can lead to difficulty in urinating.