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GENERIC NAME:
phentermine
BRAND
NAMES: Adipex-P, Obenix, Oby-Trim
DRUG CLASS AND MECHANISM:
Phentermine is in a class of drugs called
anorectics which decrease appetite by possibly
changing brain levels of serotonin. Phentermine
is a nervous system stimulator like the
amphetamines, causing stimulation, elevation of
blood pressure, and faster heart
rates.
Obesity is
usually defined as being 20% over ideal weight
with resultant increase in certain diseases
including high cholesterol levels, heart
disease, high blood pressure, gallbladder
disease, type II diabetes mellitus, hardening of
the arteries, and degenerative arthritis. Weight
loss decreases blood pressure, cholesterol
levels, and improves diabetes
control.
PRESCRIPTION:
yes
GENERIC AVAILABLE:
yes
PREPARATIONS: Tablets:
30mg, 37.5mg.
STORAGE: Phentermine should
be stored in a tight container at room
temperature.
PRESCRIBED FOR: Phentermine
is usually used as a short- term drug along with
diet and behavior modification to treat obesity.
Recently, it has been combined with diet and
fenfluramine (Pondimin) and used over longer
terms in selected obesity patients (P & P
diets) with some favorable long-term modest
weight loss.
DOSING: Phentermine should
be taken after breakfast; evening doses should
be avoided because of secondary
insomnia.
DRUG INTERACTIONS:
Phentermine should not be taken by patients with
glaucoma, hyperthyroidism, or a history of drug
abuse or psychotic illnesses. Phentermine is not
recommended in patients with high blood pressure
that is not well controlled. Patients on
phentermine should have their blood pressure
closely followed. Insulin requirements may
change in patients on phentermine; alcohol can
cause a drug interaction. Abrupt stoppage of the
drug can cause withdrawal with fatigue and
depression. Phentermine is potentially
addicting. Phentermine is not recommended for
patients with symptomatic heart disease
including rhythm problems.
SIDE EFFECTS: Side effects
include diarrhea, dry mouth, constipation, an
unpleasant taste, hives, impotence,
palpitations, high blood pressure, and fast
heart rates. Central nervous system side effects
include overstimulation, insomnia, restlessness,
tremor, and
dizziness. |
